Description:RecombinantmonoclonalantibodytoCMVglycoproteingB.ManufacturedusingAbAb’sRecombinantPlatformwithvariableregions(i.e.specificity)fromthehybridomaHCMV37.
ThischimericrabbitantibodywasmadeusingthevariabledomainsequencesoftheoriginalMouseIgG2aformat,forimprovedcompatibilitywithexistingreagents,assaysandtechniques.
SpeciesandIsotype:RabbitIgG,kappa
CloneNumber:HCMV37
UniProtAccessionNumberofTargetProtein:AlternativeName(s)ofTarget:HumancytomegalovirusglycoproteinsgB
PublishedApplication(s):NTRL;
ELISA;IHC-Fr;IF;ICC
PublishedSpeciesReactivity:CMV
Immunogen:HumanCytomegalovirusextracts.
Specificity:ThisantibodybindstohumancytomegalovirusglycoproteingB.
ApplicationNotes:ThisantibodybindstoCMVglycoproteingBandhasbeenshownhaveneutralizingactivity.
AntibodyFirstPublishedin:Tempestetal.IdentificationofframeworkresiduesrequiredtorestoreantigenbindingduringreshapingofamonoclonalantibodyagainsttheglycoproteingBofhumancytomegalovirus.IntJBiolMacromol.1995Feb;17(1):37-42.PMID:7772562
Noteonpublication:DescribescharacterisationofthestructuralrequirementsofHCMV37essentialforantigenbinding.
ProductForm
Purification:ProteinAaffinitypurified
Suppliedin:PBSwithpreservative(0.02%Proclin300)
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°C
Concentration:Seeviallabel.
Importantnote–Thisproductisforresearchuseonly.Itisnotintendedforuseintherapeuticordiagnosticproceduresforhumansoranimals.