absoluteantibody/Ab00337-6.4 Anti-Rhodopsin [Rho 1D4]/Ab00337-6.4/ 200 µg,Absolute Antibody,,Absolute Antibody,absoluteantibody,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：absoluteantibody/Ab00337-6.4 Anti-Rhodopsin [Rho 1D4]/Ab00337-6.4/ 200 µg

产品编号：Ab00337-6.4

市场价：¥5400.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>标签抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$270.00

品牌： Absolute Antibody

公司：Absolute Antibody

公司分类：

商品介绍

Description:RecombinantmonoclonalantibodytoRhodopsin.ManufacturedusingAbAb’sRecombinantPlatformwithvariableregions(i.e.specificity)fromthehybridomaRho1D4.ThisantibodywascreatedusingourproprietaryFcSilent™engineeredFcdomaincontainingkeypointmutationsthatabrogatebindingtoFcgammareceptors.

ThischimericratantibodywasmadeusingthevariabledomainsequencesoftheoriginalmouseIgG1formatforimprovedcompatibilitywithexistingreagents,assaysandtechniques.

SpeciesandIsotype:RatIgG1,FcSilent™,kappa
CloneNumber:Rho1D4
UniProtAccessionNumberofTargetProtein:P08100
AlternativeName(s)ofTarget:VisualPurple
PublishedApplication(s):RADIoimmunelabeling;WB;ELISA;IP;IF;IHC
PublishedSpeciesReactivity:Mouse;Rat;Cow;Human,Zebrafish,Amphibians
Immunogen:Bleachedbovinerodoutersegment(ROS).
Specificity:TheantibodybindstotheC-terminusofrhodopsinonthecytoplasmicsideofdiskmembranes.Theepitopehasthefollowingaminoacidsequence:"TETSQVAPA".Alimitationofthe1D4tag,however,isthatithastobeplacedattheC-terminusofaprotein.ThisisbecausetheRho1D4monoclonalantibodyrequiresafreecarboxylategroupforhighaffinitybinding.AmidationofthecarboxylgrouplowersitsimmunoreactivitytotheRho1D4antibodybyover100fold.
ApplicationNotes:TheantibodybindstotheC-terminusofrhodopsinonthecytoplasmicsideofdiskmembranes.RhodopsinisthemajorpigmentinrodphotoreceptorsandbelongstothefamilyofG-protein-coupledreceptors(GPCRs).Thelinearepitope(TETSQVAPA)canbeusedasaproteintag.
AntibodyFirstPublishedin:
Moldayetal.1983Monoclonalantibodiestorhodopsin:characterization,corss-reactivity,andapplicatoinassturcturalprobes.Biochemistry,1983;22(3):653-660PMID:6188482Noteonpublication:Describesthegenerationoftwomonoclonalantibodiesfromhybridoma.

ProductForm

Purification:ProteinAaffinitypurified
Suppliedin:PBSwithpreservative(0.02%Proclin300)
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°C
Concentration:Seeviallabel.

Importantnote–Thisproductisforresearchuseonly.Itisnotintendedforuseintherapeuticordiagnosticproceduresforhumansoranimals.

品牌介绍

Absolute Antibody于2012年在英国剑桥成立，是由英国牛津大学Hutchings博士和Barclay教授创办的第二代抗体公司，可以在两周内提供100mg级的工程化抗体，并且不含动物成分，批间差极小，消除因补体和Fc受体造成的背景，使结果更干净。该公司的成立顺应了Nature杂志为首的科学界提倡改变目前抗体供应混乱状况的时代潮流。目前提供国内的产品主要包括：

l 科研用生物仿制药抗体

l 嵌合单克隆抗体

l 用于体内实验的重组抗体

l 表位标签

l 重组非IgG同型对照

l 重组蛋白（Fc融合蛋白）

公司介绍

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