Description:RecombinantmonoclonalantibodytoOX40L.ManufacturedusingAbAb’sRecombinantPlatformwithvariableregions(i.e.specificity)fromthetherapeuticantibodyR4930(Oxelumab).ThisantibodywascreatedusingourproprietaryFcSilent™engineeredFcdomaincontainingkeypointmutationsthatabrogatebindingtoFcgammareceptors.
NOTFORTHERAPEUTICUSE-Thisisaresearch-gradebiosimilar.
SpeciesandIsotype:HumanIgG1,FcSilent™,kappa
CloneNumber:R4930(Oxelumab)
UniProtAccessionNumberofTargetProtein:PublishedApplication(s):Block,FC
PublishedSpeciesReactivity:Human
Immunogen:OxelumabbindstohumanOX40L,theligandofOX40,stimulatoryreceptorthatisexpressedonactivatedTcells,naturalkiller(NK)cellsandnaturalkillerT(NKT)cells.
Specificity:BindstohumanOX40L.
ApplicationNotes:Thisantibodybindstotheco-stimulatoryOX40L,inhibitingitsinteractionwithOX40.
ProductForm
Purification:ProteinAaffinitypurified
Suppliedin:PBSonly.
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°C
Concentration:Seeviallabel.
Importantnote–Thisproductisforresearchuseonly.Itisnotintendedforuseintherapeuticordiagnosticproceduresforhumansoranimals.