Description: Recombinant monoclonal antibody to SARS-CoV S glycoprotein. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the EBV transformed human B cell clone S217. Made with Antibody Sequences licensed from Humabs Biomed SA. Made with Antibody Sequences licensed from Humabs Biomed SA.
This chimeric rabbit antibody was made using the variable domain sequences of the original human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Species and Isotype: Rabbit IgG, kappa
Clone Number: S217
UniProt Accession Number of Target Protein: Published Application(s): ELISA; NTRL
Published Species Reactivity: SARS Virus
Immunogen: Made by immortalizing IgG-expressing B cells from recovered SARS patients.
Specificity: SARS-CoV-neutralizing hmAbs, binds to SARS-CoV S glycoprotein, inhibiting the binding of the glycoprotein to human ACE2.
Antibody First Published in: Rockx B, Corti D, Donaldson E, Sheahan T, Stadler K, Lanzavecchia A, Baric R. An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronaVirus Nat Med. 2004 Aug;10(8):871-5. Epub 2004 Jul 11. PMID:15247913
Product Form
Purification: Protein A affinity purified
Supplied in: PBS with preservative (0.02% Proclin 300)
Storage Recommendation: Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
Concentration: See vial label.
Important note – This product is for research use only. It is not intended for use in therapeutic or diagnostic
procedures for humans or animals.