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主营:工程化抗体
℡ 4000-520-616
℡ 4000-520-616
absoluteantibody/Anti-CD41 [7E3 (Abciximab)]/100 μg/Ab00282-10.6
产品编号:Ab00282-10.6
市  场 价:¥7100.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$355.00
品      牌: Absolute Antibody
公      司:Absolute Antibody
公司分类:
absoluteantibody/Anti-CD41 [7E3 (Abciximab)]/100 μg/Ab00282-10.6
商品介绍

UniProt Accession Number of Target Protein: P08514

Alternative Name(s) of Target: Integrin alpha-IIb, Integrin alpha-2b, ITGA2B, platelet glycoprotein IIb of IIb/IIIa complexImmunogen: CD41 is the integrin alpha chain 2b forming a fibrinogen receptor in heterodimeric complex with beta 3.

Specificity: Recognises human CD41.

Antibody first published in:No Authors Listed .Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty. The EPIC Investigation.N Engl J Med.PMID:8121459

Binding Curve
Flow-cytometry on human lymphocytes using Ab00282.
Binding Curve

Flow-cytometry using the anti-CD41 research biosimilar antibody Abciximab (7E3, Ab00282) Human lymphocytes were stained with an isotype control (Ab00102-23.0, panel A) or the rabbit-chimeric version of Abciximab (Ab00282-23.0, panel B) at a concentration of 1 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a AF488 conjugated donkey anti-rabbit antibody (ab150073) and cells analysed on a FACSCanto flow-cytometer.

品牌介绍

Absolute Antibody2012年在英国剑桥成立,是由英国牛津大学Hutchings博士和Barclay教授创办的第二代抗体公司,可以在两周内提供100mg级的工程化抗体,并且不含动物成分,批间差极小,消除因补体和Fc受体造成的背景,使结果更干净。该公司的成立顺应了Nature杂志为首的科学界提倡改变目前抗体供应混乱状况的时代潮流。目前提供国内的产品主要包括:

 

l  科研用生物仿制药抗体

l  嵌合单克隆抗体

l  用于体内实验的重组抗体

l  表位标签

l  重组非IgG同型对照

 

l  重组蛋白(Fc融合蛋白)


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