Description:RecombinantmonoclonalantibodytoE2Adomain.ManufacturedusingAbAb’sRecombinantPlatformwithvariableregions(i.e.specificity)fromthebone-marrowderivedphagedisplayantibodyF5.
SpeciesandIsotype:HumanIgG1,lam
BDa
CloneNumber:F5
UniProtAccessionNumberofTargetProtein:PublishedApplication(s):NTRL;crystallization
PublishedSpeciesReactivity:HumanVenezuelanEquineEncephalitisVirus
Immunogen:Thisantibodythatwasisolatedusingphagedisplayfromhumanbonemarrowdonors.
Specificity:ThisantibodybindstotheE2Adomaintoanepitopemappedtoaminoacids115to119.
ApplicationNotes:ThisantibodyhasbeenshowntohaveprotectiveeffectsinVEEVchallengeandhasbeenusedincrystallizationstudies.
AntibodyFirstPublishedin:Huntetal.AhumanizedmurinemonoclonalantibodyprotectsmiceeitherbeforeorafterchallengewithvirulentVenezuelanequineencephalomyelitisvirusJGenVirol.2006Sep;87(Pt9):2467-76.PMID:16894184
Noteonpublication:Describesthegenerationofthisantibodyfromaphagedisplaylibrary.
ProductForm
Purification:ProteinAaffinitypurified
Suppliedin:PBSwithpreservative(0.02%Proclin300)
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°C
Concentration:Seeviallabel.
Importantnote–Thisproductisforresearchuseonly.Itisnotintendedforuseintherapeuticordiagnosticproceduresforhumansoranimals.