Description:RecombinantmonoclonalantibodytoApim2.ManufacturedusingAbAb’sRecombinantPlatformwithvariableregions(i.e.specificity)fromthehybridoma21E11.
ThischimerichumanantibodywasmadeusingthevariabledomainsequencesoftheoriginalMouseIgG1format,forimprovedcompatibilitywithexistingreagents,assaysandtechniques.
SpeciesandIsotype:HumanIgG4-P,kappa
CloneNumber:21E11
UniProtAccessionNumberofTargetProtein:Q08169
PublishedApplication(s):ELISA;crystallization
PublishedSpeciesReactivity:Honeybee(Apismellifera)
Immunogen:RecombinantApim2,amajorbeevenomallergen.
Specificity:ThisantibodybindstoApim2,atasitecompetingwithcommonallergogenicIgEantibodies.
ApplicationNotes:ThisantibodycompeteswithnaturallyoccurringIgEforbindingtoApim2.AFabversionofthisantibodywasusedinaco-crystallizationstudy
AntibodyFirstPublishedin:Padavattanetal.IdentificationofaB-cellepitopeofhyaluronidase,amajorbeevenomallergen,fromitscrystalstructureincomplexwithaspecificFab.JMolBiol.2007May4;368(3):742-52
Noteonpublication:Describesthegenerationandcharacterizationofthisantibody.
ProductForm
Purification:ProteinAaffinitypurified
Suppliedin:PBSwithpreservative(0.02%Proclin300)
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°C
Concentration:Seeviallabel.
Importantnote–Thisproductisforresearchuseonly.Itisnotintendedforuseintherapeuticordiagnosticproceduresforhumansoranimals.