Description:RecombinantmonoclonalantibodytoSARS-CoVSglycoprotein.ManufacturedusingAbAb’sRecombinantPlatformwithvariableregions(i.e.specificity)fromtheEBVtransformedhumanBcellcloneS109.MadewithAntibodySequenceslicensedfromHumabsBiomedSA.MadewithAntibodySequenceslicensedfromHumabsBiomedSA.
ThischimericrabbitantibodywasmadeusingthevariabledomainsequencesoftheoriginalhumanIgG1format,forimprovedcompatibilitywithexistingreagents,assaysandtechniques.
SpeciesandIsotype:RabbitIgG,lam
BDa
CloneNumber:S109
UniProtAccessionNumberofTargetProtein:PublishedApplication(s):ELISA;NTRL
PublishedSpeciesReactivity:SARSVirus
Immunogen:MadebyimmortalizingIgG-expressingBcellsfromrecoveredSARSpatients.
Specificity:SARS-CoV-neutralizinghmAbs,bindstoSARS-CoVSglycoprotein,inhibitingthebindingoftheglycoproteintohumanACE2.
AntibodyFirstPublishedin:RockxB,CortiD,DonaldsonE,SheahanT,StadlerK,LanzavecchiaA,BaricR.Structuralbasisforpotentcross-neutralizinghumanmonoclonalantibodyprotectionagainstlethalhumanandzoonoticSevereAcuteRespiratorySyndromeCoronaViruschallenge.JOURNALOFVIROLOGY,Apr.2008,p.3220–3235PMID:18199635
ProductForm
Purification:ProteinAaffinitypurified
Suppliedin:PBSwithpreservative(0.02%Proclin300)
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°C
Concentration:Seeviallabel.
Importantnote–Thisproductisforresearchuseonly.Itisnotintendedforuseintherapeuticordiagnosticproceduresforhumansoranimals.