Description:RecombinantmonoclonalantibodytoRh(D).ManufacturedusingAbAb’sRecombinantPlatformwithvariableregions(i.e.specificity)fromthehybridomaFOG-1.
ThischimericrabbitantibodywasmadeusingthevariabledomainsequencesoftheoriginalhumanIgG1format,forimprovedcompatibilitywithexistingreagents,assaysandtechniques.
SpeciesandIsotype:RabbitIgG,kappa
CloneNumber:FOG-1
UniProtAccessionNumberofTargetProtein:Q02161
AlternativeName(s)ofTarget:Rhbloodgroup;Dantigen;RHCED;CD240D;RHDVA(TT);DIIIc;RHDel;RH;RHPII;Rh4;RhDCw;RhII;RhK562-II;RhPI1;bloodgroupRh(D)polypeptide;Rhpolypeptide2;Dantigen(DCS);RhesusDantigen;RhbloodgroupantigenEvans;RHXIII;RhesusbloodgroupDantigenalleleDIIItype7;Rh30a;RhesussystemDpolypeptide;Rhesusbloodgroup,Dantigen;RhPII;RH30;CD240Dantigen;RhesusDantigen;RHD;Rhbloodgroup,Dantigen;RH;RHP
PublishedApplication(s):ELISAPublishedSpeciesReactivity:Human
Immunogen:ThemonoclonalFOG-1anti-DantibodiesisderivedfromhyperimmunizedRh-negativeblooddonorsFo.
Specificity:RecogniseserythrocyteRh(D)allo-antigen.
AntibodyFirstPublishedin:MelamedMD1, ThompsonKM, GibsonT, Hughes-JonesNC.Requirementsfortheestablishmentofheterohybridomassecretingmonoclonalhumanantibodytorhesus(D)bloodgroupantigen.JImmunolMethods. 1987Nov23;104(1-2):245-51.PMID:2824618
Noteonpublication:Describesthederivationofmonoclonalanti-Dantibody,FOG-1,fromhyperimmunizedRh-negativeblooddonors.
ProductForm
Purification:ProteinAaffinitypurified
Suppliedin:PBSwithpreservative(0.02%Proclin300)
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°C
Concentration:Seeviallabel.
Importantnote–Thisproductisforresearchuseonly.Itisnotintendedforuseintherapeuticordiagnosticproceduresforhumansoranimals.