Description:Recombinantmonoclonalantibodytopre-fusionconfirmationofHRSVFprotein.ManufacturedusingAbAb’sRecombinantPlatformwithvariableregions(i.e.specificity)fromtheEBVtransformedhumanBcellcloneRSB43.MadewithAntibodySequenceslicensedfromHumabsBiomedSA.MadewithAntibodySequenceslicensedfromHumabsBiomedSA.
ThischimericrabbitantibodywasmadeusingthevariabledomainsequencesoftheoriginalhumanIgG1format,forimprovedcompatibilitywithexistingreagents,assaysandtechniques.
SpeciesandIsotype:RabbitIgG,lam
BDa
CloneNumber:RSB43
UniProtAccessionNumberofTargetProtein:PublishedApplication(s):IF;NTRL
PublishedSpeciesReactivity:RespiratorySyncytialVirus(RSV)
Immunogen:MadebyimmortalizingIgG-expressingBcellsfromhealthypatients.
Specificity:AntibodyisolatedashumanIgG1.NeutralisesHRSV-A2withIC50of0.219µg/ml.
AntibodyFirstPublishedin:Cortietal.Cross-neutralizationoffourparamyxoVirusesbyahumanmonoclonalantibody.Nature501,439–443(2013).PMID:23955151
ProductForm
Purification:ProteinAaffinitypurified
Suppliedin:PBSwithpreservative(0.02%Proclin300)
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°C
Concentration:Seeviallabel.
Importantnote–Thisproductisforresearchuseonly.Itisnotintendedforuseintherapeuticordiagnosticproceduresforhumansoranimals.